Scientist for Frontage Laboratories, Inc. - Exton, PA
Conduct method transfer, method development, method validation/qualification, charact, quantitation & struct elucidation; perfm high-volume bio-analyt sample analysis, data analysis QC & interpret for bio-analyt, PK, PD & ADME stud in regulated environment; draft method, study protocol & sample analysis plan; utilize & maintain analyt insts including HPLC, UHPLC, LC-MS/MS, HRMS, ICP-MS & NMR; perfm duties per SOPs & GLP regulations; present accomplishments in conferences; ident state-of-the-art tech to strengthen company’s bioanalyt capabilities; lead scientific investigations & efforts to troubleshoot assay problems.
Requirements: Ph.D. or foreign equivalent degree in Chemical, Biochemical or related field; 1 year experience as a Scientist or 1 year research experience. Required experience including HRMS charact of proteins such as antibody & antibody drug conjugates, peptide mapping, antibody drug conjugates synthesis, protein isolation & purification, solid phase extraction, liquid-liquid extraction, LC/MS method development/validation, sample analysis by immunoassay or mass spectrometry, troubleshooting, data collection & analysis. Experience can be gained while pursuing graduate degree; proficiency in HPLC, LC-MS/MS & LC-HRMS (TOF and orbitrap), ICP-MS, NMR, Analyst & BioPharma View Software.